Table 4.
Comparison of allele frequencies and number of risk alleles associated with type 2 diabetes in offspring and controls
| Offspring (n = 1671) | Controls (n = 744) | P-Value | |
| Rs10497721 | 0.09 | 0.10 | 0.918 |
| Rs1801282 | 0.87 | 0.88 | 0.363 |
| Rs4402960 | 0.29 | 0.31 | 0.355 |
| Rs10010131 | 0.56 | 0.59 | 0.152 |
| Rs7754840 | 0.33 | 0.32 | 0.559 |
| Rs13266634 | 0.70 | 0.69 | 0.594 |
| Rs564398 | 0.57 | 0.57 | 0.970 |
| Rs10811661 | 0.83 | 0.82 | 0.473 |
| Rs1111875 | 0.60 | 0.59 | 0.280 |
| Rs7903146 | 0.27 | 0.27 | 0.816 |
| Rs5219 | 0.35 | 0.37 | 0.409 |
| Rs1495377 | 0.50 | 0.50 | 0.754 |
| Rs8050136 | 0.38 | 0.37 | 0.771 |
| Rs4430796 | 0.49 | 0.48 | 0.399 |
| Rs757210 | 0.39 | 0.38 | 0.357 |
| Mean number of risk alleles | 14.5 | 14.5 | 0.977 |
| (95% CI) | (14.4-14.6) | (14.3-14.7) |
Allele frequencies are reported for the T2D risk alleles. P-values report difference in genotype trend between offspring and partners and account for family relations among the offspring by using robust standard errors.