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Gene silencing against CCL22 and the alteration of inflammatory cytokine levels. Expression of CCL22 was silenced in splenocytes after treatment with ST-miRCCL22; ST-miRCV did not affect CCL22 expression (A). Specific gene silencing against CCL22 suppressed IL-4 (B) and increased IFN-γ levels (C). One experiment, representative of three independent analyses with similar results, is shown.
