Fig. 2.

Noise (standard deviation over mean) of promoter occupancy by newly arriving TF molecules. Theoretically predicted noise was calculated according to (22) and (26), NT = 200 molecules, n = 50,000 sites, τ_3D = 0.1 ms; 0.01 < τ_res < 1.5 ms, corresponding to 0.0067 < φ < 1, T = 300 s; Simulated noise was obtained by taking the standard deviation over the mean of 3,000 independent entries, for each value of τ_res that was simulated. Inset Simulated vs. theoretically predicted noise in occupancy of the cognate binding site, with a linear fit showing good agreement