Table 1.
Effect of escitalopram on TBARS in nmol/mg tissue protein and Catalase enzyme activity in μmol/min/mgtissue protein in frontal cortices and nucleus accumbens homogenates.
| Substance | CONTROL | CMS WITHOUT TREATMENT | CMS+ ESC | |||
|---|---|---|---|---|---|---|
| PfCx | NAc | PfCx | NAc | PfCx | NAc | |
| TBARS in nmol/mg tissue protein | 1.9±0.51 | 1.17±0.17 | 6.2±0.69* | 7.53±0.82* | 1.2±0.3** | 1.08±0.31** |
| Catalase enzyme activity in μmol/min/mgtissue protein | 225.5±8.3 | 110.3± 3.36 | 12.0±0.7* | 0.11 ± 0.02* | 300.4±27.8** | 111.5 ± 0.85** |
The results are expressed as means ± S.D. (N = 12 for each group).