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. 2011 Feb 28;61(584):e125–e133. doi: 10.3399/bjgp11X561249

Table 3.

Cost-effectiveness studies undertaken of interventions that included physical activity counselling or intervention within primary care or the community (published from 2002 to 2009).

Outcome

Study details and quality Objective; economic perspective Study type; economic analysis type Interventions (I) and comparison (C) Participants, number in each group Follow-up duration (months) Annual cost per participant to become active, (€at time of study) [inflated to June 2008] Cost of shifting to active categorya, (€at time of study) [inflated to June 2008] Cost per QALY (€ at time of study) [inflated to June 2008]
UK Beam Trial Team,17 UK: Excellent Primary care, multifaceted intervention for low back pain; health funder, 2000–2001 RCT; CUA I1: exercise programme; I2: spinal manipulation; I3: combined; C: usual care Participants consulting GP for low back pain: I1: 297 12 £8235b (€13 423) [€15 860]
I2: 342
I3: 322
C: 326

Cochrane et al,18 UK: Excellent Primary care/community water exercise programme; societal costs, 2002 RCT; CEA I1: water-based exercise, C: usual care Older participants with hip and/or knee OA: I1: 153 12 £5008c (€7963) [€9160]
C: 159

Hurley et al,19 UK: Excellent Primary care, Knee rehabilitation; societal costs, 2003 Cluster RCT; CEA, CUA I1: individual rehabilitation,d I2: group-based rehabilitation,d C: usual primary care Participants ≥50 years attending primary care for mild/moderate/severe knee pain, duration >6 months: I1: 146 6 Usual care produced greater QALY gain (0.0096) than individual rehabilitation (−0.0034) and group rehabilitation (0.0057), despite ‘functional improvements’ with exercise interventions
I2: 132
C: 140

Hollinghurst et al,20 UK: Fair Primary care; societal perspective, 2005 4 × 2 factorial RCT; CEA I1: short-course Alexander technique, I2: long-course Alexander technique, I3: massage, C: usual care groups; All also randomised into with or without GP exercise script and practice nurse exercise counselling Participants with chronic or recurrent low back pain: I1: 144 12 £2847 (€4157) [€4577] (exercise counselling and prescription for exercise compared with usual care)
I2: 144
I3: 147
C: 144

Gusi et al,21 Spain: Poor Primary care, supervised walking programme; health funder, 2005 RCT; CUA I1: walking-based, supervised programme (3 × 50 min/week), C: usual care Women, ≥60 years with moderate depression or overweight: I1: 64 6 €311 [€348]
C: 63

Handley et al,22 US: Fair Primary care-based automated telephone support; direct programme costs, June 2003 to December 2004 RCT; CEA, CUA I1: automated telephone surveillance/support, nurse care management, C: usual care Adult English-, Spanish-, Cantonese-speaking primary care participants with type 2 diabetes: I1: 112 12 US $558e (€463) [€551] US $65 167 (€54 089), [€64 346]
C: 114

Sevick et al,23 US: Excellent Community, physical activity counselling; health funder, 2004 RCT; CEA I1: telephone-based feedback on PAf, I2: print-based feedback on PA, C: contact control Sedentary adults (18-65 years): I1: 80 12 $3967 (€3174) [€3673] (phone group); $955 (€764) [€884] (print group)
I2: 81
C: 78

Munro et al,24 UK: Poor Primary care, exercise class; health funder, 2003/2004 Cluster RCT; CUA, CEA I1: free, 2 × weekly (45 min) community-based exercise class, C: usual care Participants ≥65 years assessed by survey as being in least-active four-fifths of the population: I1: 2283 24 €17 174 [€19 425]
C: 4137

Dzator et al,25 Australia: Fair Physical activity/nutrition programme in community setting; direct programme costs RCT; CEA I1: high-level, interactive group sessions, I2: low-level, mailed intervention, C: no intervention Couplesh (mean age 28–31 years): I1: 47 couples 12 No significant effect difference between groups observed regarding the activity level: exercise days per week AUS $460.44 (€267) [€350] (high level); AUS $458.61 (€266) [€349] (low level)
I2: 47 couples
C: 43 couples

Elley et al,11 New Zealand: Excellent Primary care exercise counselling/prescription; societal costs, 2001 Cluster RCT; CEA I1: Green Prescription, counselling in general practice, C: usual care Less active primary care participants (40–79 years): I1: 451 12 €825 [€957] (activity level 5 × 30 min/week) NZ $1756g (€825) [€957]
C: 427

Dalziel et al,10 New Zealand: Excellent Primary care exercise counselling/prescription data from Elley's study;11 2001 costs Cluster RCT; CUA I1: Green Prescription, counselling in general practice, C: usual care Less-active primary care participants (40–79 years): I1: 451 12 NZ$2053 (€965) [€1120]
C: 427

Isaacs et al,26 UK Good Primary care referral to exercise programmes; health funder, 2002 costs RCT; CEA I1: supervised, gym-based exercise classes,i I2: instructor-led walking programme,i C: advice and information only Physically inactive 40–74 year olds with at least one cardiovascular risk factor: I1 317 12 I1: £19 500 (€31 005) [€35 665]; I2: £47 500 (€75 525) [€86 877]
I2: 311
C: 315

Elley et al,27 New Zealand: Excellent Primary care exercise counselling/prescription; societal costs, 2008 RCT; CEA I1: enhanced Green Prescription, counselling in primary care, C: usual care Physically inactive 40–74-year-old women 24 NZ $687 [€331] sustained at 12 months; NZ $1407 [€678] sustained at 24 months
a

Undertaking at least 150 minutes of at least moderate-intensity physical activity per week.

b

Exercise programme component only.

c

20% (n = 65) missing values for EuroQol-5D (EQ-5D) imputed by regression based on age, sex, and EuroQol-Visual Analogue Scale (EQ-VAS).

d

12 supervised sessions, 2 × weekly for 6 weeks (40 minutes to 1 hour) including information giving and exercises.

e

Cost to achieve a 10% increase in the proportion of participants achieving moderate or vigorous physical activity.

f

No significant difference between phone and control group at 12 months for PA measures.

g

Programme cost of shifting one person from sedentary to active category.

h

Variable proportion of participants reported as sufficiently active at baseline.

i

Ten-week (2–3 times per week).

CEA = cost-effectiveness analysis. CUA = cost-utility analysis. OA = osteoarthritis. PA = physical activity. QALY = quality-adjusted life-year. RCT = randomised controlled trial.