Fig. 1.

Schematic of our biochip working principle: the biochip consists of a fluidic channel and a curved waveguide buried in the glass. A Gaussian beam emitted by a single mode fiber is coupled into the biochip waveguide and diverges to illuminate a small length of the fluidic channel. When objects pass through the fluidic channel, they momentarily distort the beam intensity profile. The light coming out of the biochips is then refocused onto a four-quad detector to monitor small changes of intensity.