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Fatigue Severity Scale (FSS) scores across time for total sample and by treatment group. Effect size estimates (Cohen’s d) for 6- and 12-month change in FSS scores compared to pretreatment baseline: total sample = 0.28 at 6 months and 0.26 at 12 months; leuprolide group = −0.004 at 6 months and 0.25 at 12 months; bicalutamide group = 0.57 at 6 months and 0.31 at 12 months
