Table 2.
Degarelix 240/80 mg | Degarelix 240/160 mg | Pooled Degarelix | Leuprolide 7.5 mg | |
---|---|---|---|---|
Baseline: | ||||
No. | 191 | 183 | 374 | 184 |
Mean (SD) | 405 (19.8) | 401 (18.5) | 403 (19.2) | 403 (18.8) |
Day 3: | ||||
No. | 188 | 181 | 369 | 181 |
Mean (SD) | 409 (22.8) | 402 (18.4) | 405 (21.0) | 403 (21.8) |
Change (SD) | 4.43 (15.4) | 0.576 (16.6) | 2.54 (16.1) | 0.198 (17.5) |
Mean % change | 1.06 | 0.148 | 0.612 | 0.0132 |
End of trial: | ||||
No. | 191 | 185 | 376 | 184 |
Mean (SD) | 419 (21.9) | 413 (20.6) | 416 (21.4) | 417 (22.3) |
Change (SD) | 14.1 (18.4) | 11.9 (15.9) | 13.0 (17.2) | 14.0 (20.4) |
Mean % change | 3.46 | 2.94 | 3.21 | 3.45 |
Patients with baseline QRS greater than 120 msec were excluded from the QTc analysis.