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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Diabetologia. 2010 Dec 29;54(3):583–593. doi: 10.1007/s00125-010-2026-z

Table 1.

Time course expression of islet transcription factors

Transcription factor Age (days)

2 7 9 11 13 15 21 28
Mafa 0.09±0.06* 0.07±0.03* 0.43±0.02* 0.38±0.05* 0.41±0.02* 0.42±0.05* 0.22±0.08* 0.48±0.07
Pdx1 0.12±0.06* 0.62±0.24 2.17±0.36 1.97±0.69 1.93±0.52 0.54±0.14 0.24±0.07* 0.44±0.1
Neurod1 0.12±0.09* 0.58±0.08 4.4±0.15* 3.18±0.29* 4.22±1.01* 1.24±0.18 0.63±0.16 1.38±0.16
Nkx6-1 0.03±0.02* 0.22±0.09* 0.66±0.02 0.59±0.04 0.82±0.13 0.61±0.18 1.09±0.15 0.82±0.08
Mafb 0.62±0.32 3.25±0.51* 15.51±3.95* 14.24±2.08* 19.3±1.91* 4.96±0.94* 2.78±0.91* 4.49±0.8*

Mean ± SEM;

*

p<0.05

Values are fold change with respect to adult islets