TABLE 7.

BRCA 1 AND BRCA2 PATENTS

US Patent	Nature of Claims	Assignee	US Licensee
5654155	Consensus cDNA sequence for BRCA1, method for detecting BRCA1 mutations	OncorMed	Rights acquired by Myriad
5622829	Mutant allele probes and methods for BRCA1	University of California	OncorMed (acquired by Myriad)
5693473	BRCA1 mutations	Myriad Genetics; Centre du Recherche du Chul; Tokyo Cancer Institute	Myriad Genetics
5709999	Method for detecting BRCA1 mutations	Myriad Genetics; Centre du Recherche du Chul; Tokyo Cancer Institute	Myriad Genetics
5710001	Method for detecting BRCA1 mutations in tumors	Myriad Genetics, University of Utah Research Foundation, and the United States of America	Myriad Genetics
5747282	cDNA sequence for BRCA1, cloning vectors containing BRCA1 cDNA, kit for detecting mutations in BRCA1, and method for screening for therapeutics for cells with BRCA1 mutations	Myriad Genetics, University of Utah Research Foundation, and the United States of America	Myriad Genetics
5750400	cDNA sequence for BRCA1 and methods for detecting BRCA1 mutations	OncorMed	Rights acquired by Myriad
5753441	Method and kit for detecting BRCA1 germline mutations	Myriad Genetics, University of Utah Research Foundation, and the United States of America	Myriad Genetics
5837492	BRCA2 sequence and methods	Myriad Genetics, Endo Recherche, HSC (Hospital for Sick Children) Research & Development Limited Partnership, and Trustees of the University of Pennsylvania	Myriad Genetics
6045997	BRCA2 sequences and methods	Duke University and Cancer Research Campaign (UK)	Expired
6051379	Probes, methods, and kits for detecting BRCA2 mutations and rearrangements	Myriad Genetics, University of Utah Research Foundation, and the United States of America	Myriad Genetics
6130322	cDNA sequence for segments of BRCA1	Gene Logic	N/A
6162897	Amino acid sequence translated from BRCA1	Myriad Genetics, University of Utah Research Foundation, and the United States of America	Myriad Genetics
6686163	BRCA1 mutations and cloning vectors containing mutations	Gene Logic	N/A
6720158	BRCA1 sequence for splicing variations	Philadelphia Health & Education Corp. (now assigned to Drexel University, Personal communication with Drexel University Office of Technology Commercialization)	Unlicensed
6838256	BRCA1 consensus coding sequences, mutations, vector comprising sequence, methods for detecting mutations	Gene Logic	N/A
6951721	Method for determining functional sequence variations in BRCA1	Gene Logic	N/A

Duke University researchers requested licensing information from Gene Logic but to date have not received licensing information.

Information compiled by authors.