Figure 1.
Potential chemoprevention for gliomas. Inherited cancer syndromes with gliomas include the Li-Fraumeni syndrome (119), melanoma-astrocytoma syndrome (120, 121), neurofibromatosis 1 (122) and 2 (123), Turcot’s syndrome (124, 125) and BRCA syndrome (126). The various studies describing the individuals with increased chromosome breaks and genetic polymorphisms predisposing to gliomas have been recently reviewed (1). NSAIDs: non steroidal anti-inflammatory drugs; DFMO: alpha-difluoromethylorinithine.