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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Biochim Biophys Acta. 2010 Jan 15;1804(5):1041–1048. doi: 10.1016/j.bbapap.2010.01.006

Figure 3. Pathway of nucleotide binding.

Figure 3

The two-step sequence for nucleotide binding is shown with structures of the open E.DNA complex (tko.pdb) and the closed F.DNA.dNTP complex (tk5.pdb). The structure of the open E.DNA.dNTP complex is not known and is modeled here by placing dNTP into the empty E.DNA complex.