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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Biochim Biophys Acta. 2010 Jan 15;1804(5):1041–1048. doi: 10.1016/j.bbapap.2010.01.006

Figure 5. Alpha-thio nucleotide.

Figure 5

The structure of the dNTP-αS(Sp) is shown with the sulfur represented by the yellow sphere. Also shown is the residue K522 which forms a bond to the Sp oxygen on the α-phosphate and may cause steric effects upon sulfur substitution. The nucleotide is shown in magenta and the metal ions A and B are gray. Drawn from 1T7P.pdb.