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. 2011 Mar 2;6(3):e17030. doi: 10.1371/journal.pone.0017030

Table 5. Overview of different published estimates of QALDs lost due to ILI, for sources which presented data or interpretation of that data.

Study QALY weight Worst day/disease Background QALY weight Duration of disease (days) QALD loss Sample size Method Focus group Age group
(Griffin, Perry, & Fleming, 2001) −0.066 0.817 2.48 2.19* 21 EQ-5D Patients (within 3 months after onset) 18+
(Griffin, Perry, & Fleming, 2001) −0.263 0.72 2.48 2.45* 8 EQ-5D GPs Unknown
(O'Brien, Goeree, Blackhouse, Smieja, & Loeb, 2003) Changed by day Not reported Not reported Not reported 920 in placebo (639 with influenza Likert score transferred to VAS ILI patients (clinical trails antivirals GSK) 18–64
(Turner et al., 2003) Changed by day Not reported Not reported Not reported See O'Brien at al Converted the Likert scores into VAS scores converted those into time-trade off scores ILI patients (clinical trails antivirals GSK) 18–64
(Rothberg, Bellantonio, & Rose, 2003) 0.25 1 Not reported Not reported 15 HUI-3 Patients Working adults
(Prosser et al., 2006) Not reported Not reported Not reported 1.83 Not reported Time trade off Parents of children Children
(Siddiqui & Edmunds, 2008) VAS scores as presented by O'Brien et.al 0.85 Not reported 1.68 for influenza ILI1.57 for non-influenza ILI See O'Brien et.al. VAS scores substracted from the baseline ILI patients 18–64
(Sander et al., 2010) QALY scores as presented by Turner et.al. Not reported Not reported 5.33 (0–19 yrs)6.35 (20–64 yrs) 10.69 (65+) See O'Brien et.al Uses published QALY weights and combines this with unpublished disease duration ILI patients 18–64