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. 2011 Mar 2;6(3):e16986. doi: 10.1371/journal.pone.0016986

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Campbell et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Example of a pair (Pair 17) whose consensus env sequences were unlinked, with linkage subsequently determined by single molecule (SM) env sequences. The linkage criteria used during adjudication are displayed in the table. Three linked sequences from the HIV-1 infected partner, PP17A variant 1, along with the sequences from the seroconverting partner PP17B are bounded by the solid rectangle. Unlinked sequences from the HIV-1 infected partner, PP17A variant 2 are delineated by the dotted rectangle.