Table 2. H. pylori -CSAs and CagA seropositivity and the risk of stomach adenocarcinoma overall, cardia site and non-cardia site.
Stomach adenocarcinoma | Cardia adenocarcinoma | Non-cardia adenocarcinoma | ||||||||
Serological test results | Case | Control | OR*(95% CI) | Case | Control | OR*(95% CI) | Case | Control | OR*(95% CI) | |
Hp-CSAs antibodies | Negative | 20 | 76 | Ref. | 12 | 21 | Ref. | 6 | 51 | Ref. |
Positive | 39 | 41 | 4.1 (1.9–8.5) | 3 | 9 | 0.5 (0.1–2.8) | 35 | 30 | 17.1 (4.0–72.9) | |
CagA antibodies | Negative | 19 | 70 | Ref. | 11 | 19 | Ref. | 7 | 49 | Ref. |
Positive | 40 | 47 | 3.5 (1.7–7.1) | 4 | 11 | 0.6 (0.2–2.5) | 34 | 32 | 10.9 (3.2–36.9) | |
Hp-CSAs – CagA antibodies | Hp-CSAs and CagA antibodies negative | 15 | 61 | Ref. | 10 | 18 | Ref. | 4 | 41 | Ref. |
Hp-CSAs or CagA antibodies positive | 44 | 56 | 3.3 (1.6–6.7) | 5 | 12 | 0.8 (0.2–2.7) | 37 | 40 | 9.7 (2.9–32.9) | |
Hp-CSAs and CagA antibodies positive | 35 | 32 | 5.5 (2.3–12.9) | 2 | 8 | 0.3 (0.03–2.6) | 32 | 22 | 48.5 (5.8–407.4) |
* Odds ratios (ORs) were derived from conditional logistic regression models.