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. 2011 Mar 2;6(3):e17404. doi: 10.1371/journal.pone.0017404

Table 2. H. pylori -CSAs and CagA seropositivity and the risk of stomach adenocarcinoma overall, cardia site and non-cardia site.

Stomach adenocarcinoma Cardia adenocarcinoma Non-cardia adenocarcinoma
Serological test results Case Control OR*(95% CI) Case Control OR*(95% CI) Case Control OR*(95% CI)
Hp-CSAs antibodies Negative 20 76 Ref. 12 21 Ref. 6 51 Ref.
Positive 39 41 4.1 (1.9–8.5) 3 9 0.5 (0.1–2.8) 35 30 17.1 (4.0–72.9)
CagA antibodies Negative 19 70 Ref. 11 19 Ref. 7 49 Ref.
Positive 40 47 3.5 (1.7–7.1) 4 11 0.6 (0.2–2.5) 34 32 10.9 (3.2–36.9)
Hp-CSAs – CagA antibodies Hp-CSAs and CagA antibodies negative 15 61 Ref. 10 18 Ref. 4 41 Ref.
Hp-CSAs or CagA antibodies positive 44 56 3.3 (1.6–6.7) 5 12 0.8 (0.2–2.7) 37 40 9.7 (2.9–32.9)
Hp-CSAs and CagA antibodies positive 35 32 5.5 (2.3–12.9) 2 8 0.3 (0.03–2.6) 32 22 48.5 (5.8–407.4)

* Odds ratios (ORs) were derived from conditional logistic regression models.