Table 3. p15a plasmid loss with no selection detected in spleens recovered from moribund mice.
Mouse | Total CFUa (from spleen) | AmpS CFU | Plasmid Lossb |
1- pdapA | 100 | 5 | 5% |
2- pdapA | 100 | 2 | 2% |
3- pdapA | 80 | 3 | 3.75% |
Combined | 280 | 10 | 3.5% |
1- pACYC-177 | 100 | 1 | 1% |
2- pACYC-177 | 60 | 1 | 1.66% |
3- pACYC-177 | 97 | 1 | 1.03% |
Combined | 257 | 3 | 1.17% |
a: CFU: Colony forming units of Y. pestis KIM D27.
b: Amps/total CFU×100.