Table 2. Specific antibody detection of expressed proteins in penile tumours with known HPV status.
| Type of antibody | Positive antibody detection (%) | |||
| All tumours | HPV-positive tumours | HPV-negative tumours | P value | |
| pEGFR1 | 26/100 (26) | 9/57 (16) | 17/43 (40) | 0.0143 |
| HER3 m2 | 83/96 (86) | 53/56 (95) | 30/40 (75) | 0.0128 |
| HER4 m | 11/85 (13) | 8/48 (17) | 3/37 (8) | 0.3348 |
| pAktn3 | 47/98 (48) | 30/57 (53) | 17/41 (42) | 0.3752 |
| pAktcyt4 | 68/100 (68) | 38/57 (67) | 30/43 (70) | 0.9104 |
| Akt1n | 56/101 (55) | 29/57 (51) | 27/44 (62) | 0.3956 |
| Akt1cyt | 40/101 (40) | 25/57 (44) | 15/44 (34) | 0.4294 |
| PTEN | 37/94 (39) | 23/54 (43) | 14/40 (35) | 0.5951 |
P values show difference between HPV-positive and negative tumours.
1
p, phosphorylated, active protein.
2
m, membranous expression.
3
n, nuclear expression.
4
cyt, cytoplasmic expression.