Table 3.

Multivariate logistic regression model for renal measures in the Pittsburgh EDC Pulse Wave Analysis study population

	Model 1a			Model 2b			Model 3b
	Microalbuminuriac			GFR < 60 ml/min/1.73 m2			Cystatin C ≥ 1.0 mg/l
Variable	OR	95% CI	p-value	OR	95% CI	p-value	OR	95% CI	p-value
SEVR	0.35	0.17–0.73	.005	0.44	0.22–0.89	.02	0.31	0.13–0.73	.007
eGDR	0.52	0.30–0.89	.017	---	---	---	---	---	---
Heart Rate	0.72	0.38–1.38	.32	0.42	0.20–0.88	.02	0.20	0.07–0.57	.003
ACEI/ARB Use	---	---	---	3.57	1.18–10.8	.02	5.65	1.21–26.4	.03
Hypertension	---	---	---	---	---	---	6.35	1.88–21.5	.003

Odds Ratios are per standardized unit.

^aVariables available to Model 1: age, SEVR, systolic BP, diastolic BP, eGDR, WHR, BMI, heart rate, ACEI/ARB use, HDL-cholesterol, non-HDL-cholesterol, smoking history, anti-lipidemic agent use

^bVariables available to Models 2 & 3: Model 1 variables (except age) + hypertension status (BP>130/80 or medication)

^cMicroalbuminuria vs. Normoalbuminuria

Abbreviations: SEVR, subendocardial viability ratio; eGDR, estimated glucose disposal rate; ACEI/ARB, ACE inhibitor/Angiotensin II receptor blocker; BP, blood pressure; BMI, body mass index; WHR, waist-to-hip ratio