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. 2010 Sep 1;9(17):3534–3551. doi: 10.4161/cc.9.17.12908

Figure 2.

Figure 2

Chloroquine rescues the expression of phospho-Cav-1 (pY14) in activated HIF1a and IKBKE transfected fibroblasts. hTERT-BJ1 fibroblasts recombinantly expressing activated HIF1a or IKBKE were incubated with chloroquine for 24 or 48 hours and then subjected to immunoblot analysis with antibodies directed against phospho-Cav-1 (pY14). Note that treatment with chloroquine rescues the expression of phospho-Cav-1 (pY14) in both fibroblast cell lines. Immunoblotting with beta-actin is shown as a control for equal loading.