Table 2.
Proteomic analysis of IKBKE-transfected fibroblasts
| Fold change (IKBKE/pBABE) | Accession number | Protein spot # | |
| Glycolytic Enzymes and Metabolism Related Proteins | |||
| Iron-sulfur cluster scaffold homolog (E. coli) (ISCU2) | 1.56 | gi|56699456 | 3 |
| Phosphorylase, glycogen; brain (PYGB) | 1.46 | gi|1172226 | 8 |
| Enolase 1, (alpha) (ENO1) | 1.41 | gi|4503571 | 30 |
| Enolase 1, (alpha) (ENO1) | 1.38 | gi|4503571 | 31 |
| Enolase 1, (alpha) (ENO1) | 1.33 | gi|4503571 | 29 |
| Uracil DNA-glycosylase/Glyceraldehyde-3-phosphate dehydrogenase; Aging-associated gene 9 protein (UDG/GAPDH) | 1.40 | gi|35053; gi|31645; gi|54303910 | 35 |
| Uracil DNA-glycosylase/Glyceraldehyde-3-phosphate dehydrogenase; Aging-associated gene 9 protein (UDG/GAPDH) | 1.38 | gi|35053; gi|31645; gi|54303910 | 33 |
| ATP citrate lyase (ACLY) | 1.37 | gi|38569421 | 4 |
| ATP citrate lyase (ACLY) | 1.37 | gi|38569421 | 5 |
| Pyruvate kinase, muscle isoform (PKM2) | 1.35 | gi|114657944 | 26 |
| Lactate dehydrogenase B (LDHB) | 1.33 | gi|49259209 | 32 |
| Proteins Associated with the Stress Response | |||
| Chaperonin containing TCP1, subunit 7 (eta) (CCT7) | 1.43 | gi|5453607 | 25 |
| Chaperonin containing TCP1, subunit 4 (delta) (CCT4) | 1.41 | gi|119620391 | 27 |
| Heat shock 60 kDa protein 1 (Chaperonin) (HSPD1) | 1.35 | gi|77702086 | 20 |
| Chaperonin containing TCP1, subunit 3 (gamma) (CCT3) | 1.34 | gi|14124984 | 23 |
| Chaperonin containing TCP1, subunit 5 (epsilon) (CCT5) | 1.33 | gi|24307939 | 21 |
| Chaperonin containing TCP1, subunit 6A (zeta1) (CCT6A) | 1.33 | gi|121490543 | 24 |
| T-complex protein 1 (TCP1) | 1.33 | gi|57863257 | 22 |
| Peroxiredoxin 4 (PRDX4) | 1.33 | gi|119587270 | 1 |
| Heterogeneous Nuclear Ribonucleoproteins, RNA Splicing and DNA Repair | |||
| XP (xeroderma pigmentosum) associated binding protein 2 (XAB2) | 1.47 | gi|14250630 | 37 |
| CCHC-type zinc finger, nucleic acid binding protein (CNBP) | 1.38 | gi|119599682 | 38 |
| Far upstream element (FUSE) binding protein 1 (FUBP1) | 1.35 | gi|119626762 | 17 |
| KH-type splicing regulatory protein (KHSRP); FUSE-binding protein 2 (FUBP2) | 1.35 | gi|2055427 | 9 |
| Heterogeneous nuclear ribonucleoprotein K (HNRNPK) | 1.37 | gi|55958547 | 19 |
| Tamoxifen-Resistance and Multi-Drug Resistance | |||
| Major vault protein (MVP) | 1.69 | gi|119600392 | 12 |
| Nucleolin (NCL) | 1.58 | gi|119591368 | 10 |
| Other | |||
| Integrin beta1 binding protein 1 (ITGB1BP1) | 1.80 | gi|119621396 | 11 |
| Actin related protein 2/3 complex subunit 2 (ARPC2) | 1.41 | gi|5031599 | 36 |
| Valosin-containing protein (VCP) | 1.40 | gi|6005942 | 14 |
| Staphylococcal nuclease and tudor domain containing 1 (SND1) | 1.39 | gi|77404397 | 6 |
| Eukaryotic translation elongation factor 2 (EEF2) | 1.37 | gi|4503483 | 7 |
| Vimentin (VIM) | 1.34 | gi|62414289 | 28 |