Fig. 3.

Lumican consistently reduces tumor growth in vivo Equal numbers of lumican-overexpressing MCA102 fibrosarcoma and Pan02 pancreatic adenocarcinoma cells or their corresponding control counterparts were injected in triplicate into syngenic C57BL/6 mice. (a) Tumor volumes were calculated daily and are reported as the average for each day relative to the first day after inoculation that tumors appeared. Data is the average (+/-SEM) of three independent experiments. (* indicates p < .05, Mann–Whitney rank sum test). (b) Tumor masses were recorded at time of removal. Data is the final tumor mass (mg) for each tumor. Midlines represent mean mass. (* indicates p < .05, Mann–Whitney rank sum test). (c) Photos depicting the actual tumors from each of three independent experiment are shown