Table 5.
Activity of enzymatic hydrolysed collagen (EHC) (Colatech®) and glucosamine sulfate (GS) on joint improvement assessment
| Glucosamine sulphate | Enzymatic hydrolyzed collagen | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| (Colatech®) | ||||||||||
| M | SD | Me | Range | No. | M | SD | Me | Range | No. | |
| Visit 2 (day 0) | ||||||||||
| Total painful joints2 | 2.4 | 1.5 | 2.0 | 0.0–7.0 | 46 | 2.8 | 1.9 | 2.0 | 0.0–7.0 | 47 |
| Total swollen joints1,2 | 1.1 | 1.1 | 1.0 | 0.0–4.0 | 46 | 0.9 | 1.0 | 1.0 | 0.0–4.0 | 47 |
| Score index, painful joints1,2 | 3.4 | 2.1 | 3.0 | 0.0–9.0 | 46 | 4.5 | 3.1 | 4.0 | 0.0–11.0 | 47 |
| Score index, swollen joints2 | 1.3 | 1.3 | 1.0 | 0.0–5.0 | 46 | 1.3 | 1.5 | 1.0 | 0.0–8.0 | 47 |
| Visit 3 (day 15) | ||||||||||
| Total painful joints2 | 2.3 | 1.5 | 2.0 | 0.0–7.0 | 46 | 2.7 | 1.7 | 2.0 | 0.0–7.0 | 47 |
| Total swollen joints1,2 | 1.0 | 1.1 | 1.0 | 0.0–4.0 | 46 | 1.1 | 1.1 | 1.0 | 0.0–4.0 | 47 |
| Score index, painful joints1,2 | 3.3 | 2.1 | 3.0 | 0.0–8.0 | 46 | 4.1 | 2.7 | 4.0 | 0.0–11.0 | 47 |
| Score index, swollen joints2 | 1.3 | 1.4 | 1.0 | 0.0–5.0 | 46 | 1.4 | 1.5 | 1.0 | 0.0–8.0 | 47 |
| Visit 4 (day 30) | ||||||||||
| Total painful joints2 | 2.4 | 1.3 | 2.0 | 0.0–6.0 | 46 | 2.3 | 1.7 | 2.0 | 0.0–7.0 | 47 |
| Total swollen joints1,2 | 1.1 | 1.1 | 1.0 | 0.0–3.0 | 46 | 0.9 | 1.0 | 1.0 | 0.0–4.0 | 47 |
| Score index, painful joints1,2 | 3.2 | 1.6 | 3.0 | 0.0–7.0 | 46 | 3.1 | 2.4 | 3.0 | 0.0–9.0 | 47 |
| Score index, swollen joints2 | 1.2 | 1.3 | 1.0 | 0.0–4.0 | 46 | 1.1 | 1.3 | 1.0 | 0.0–7.0 | 47 |
| Visit 5 (day 60) | ||||||||||
| Total painful joints2 | 2.1 | 1.0 | 2.0 | 0.0–5.0 | 46 | 1.9 | 1.5 | 1.0 | 0.0–6.0 | 47 |
| Total swollen joints1,2 | 1.0 | 1.0 | 1.0 | 0.0–4.0 | 46 | 0.6 | 0.9 | 0.0 | 0.0–4.0 | 47 |
| Score index, painful joints1,2 | 2.6 | 1.1 | 3.0 | 0.0–5.0 | 46 | 2.3 | 1.9 | 2.0 | 0.0–8.0 | 47 |
| Score index, swollen joints2 | 1.1 | 1.1 | 1.0 | 0.0–4.0 | 46 | 0.7 | 1.0 | 0.0 | 0.0–4.0 | 47 |
| Visit 6 (day 90) | ||||||||||
| Total painful joints2 | 1.8 | 0.9 | 2.0 | 0.0–4.0 | 46 | 1.6 | 1.3 | 1.0 | 0.0–5.0 | 47 |
| Total swollen joints1,2 | 0.6 | 0.8 | 0.5 | 0.0–3.0 | 46 | 0.5 | 0.8 | 0.0 | 0.0–4.0 | 47 |
| Score index, painful joints1,2 | 2.0 | 1.1 | 2.0 | 0.0–4.0 | 46 | 1.7 | 1.4 | 1.0 | 0.0–6.0 | 47 |
| Score Index, swollen joints2 | 0.7 | 0.9 | 0.5 | 0.0–3.0 | 46 | 0.5 | 0.8 | 0.0 | 0.0–4.0 | 47 |
M median, ME median range, SD standard deviation, No. number of joints, GLM generalized linear model
1Statistically significant differences were found for the follow-up values between the two groups (glucosamine vs. Colatech®) (GLM, repeated measures; p < 0.05).
2Statistically significant differences were found for the follow-up values in each group for each treatment (GLM, repeated measures; p < 0.05).
No statistical significant differences were found for the follow-up values in each visit between two groups (GLM, repeated measures; p < 0.05)