Table 1.
Characteristics of the populations studied.
| Healthy subjects (n = 20) | All COPD (n = 19) | COPD stage 2 (n = 12) | COPD stage 3–4 (n = 7) | |
|---|---|---|---|---|
| Gender m/f (n) | 5/15 | 13/6 | 7/5 | 6/1 |
| Age, years | 41 (23–58) | 65 (54–72) | 67 (54–72) | 63 (55–69) |
| Height, cm | 168·3 (153–184) | 171·5 (151–190) | 168·8 (158–180) | 176·0 (151–190) |
| Weight, kg | 70·8 (50–92) | 82·6 (47–114) | 87·8 (57–114) | 73·7 (47–100) |
| Body mass index, kg m−2 | 24·9 (21·1–30·5) | 28·1 (20·6–43·3) | 30·8 (21·7–43·3) | 23·5 (20·6–27·7) |
| FVC, l | 4·4 (3·1–5·8) | 3·5 (1·8–4·7) | 3·3 (1·9–4·7) | 3·7 (1·8–4·7) |
| FVC, % of predictedxya | 103·1 (86·5–135·5) | 87·5 (67·8–125·2) | 89·9 (72·2–125·2) | 83·3 (67·8–95·4) |
| FEV1, l | 3·5 (2·4–4·8) | 1·7 (0·5–2·9) | 1·9 (1·1–2·9) | 1·3 (0·5–1·8) |
| FEV1, % of predicteda | 98·6 (78·4–124·7) | 53·0 (23·1–79·7) | 62·5 (50·5–79·7) | 36·6 (23·1–46·9) |
| FEV1/FVC | 0·79 (0·72–0·92) | 0·49 (0·28–0·66) | 0·57 (0·34–0·66) | 0·35 (0·28–0·41) |
| GOLD stage 2/3/4 (n) | NA | 12/5/2 | 12/0/0 | 0/5/2 |
| Pack years | NA | 52 (20–100) | 49 (20–100) | 57 (30–100) |
Parameters expressed as mean (range) unless otherwise stated.
COPD, chronic obstructive pulmonary disease; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s; GOLD, global initiative for chronic obstructive lung disease; NA, not applicable.
a
Finnish reference values (Viljanen et al., 1982).