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. 2010 Dec 15;9(24):4884–4892. doi: 10.4161/cc.9.24.14156

Figure 4.

Figure 4

The normal CD5− B cell compartment in CLL patients retains greater BAFF-R expression than the malignant clone. (A) Representative histogram of normal peripheral blood B cells (far right histogram) and malignant CLL cells (center and left histograms) isolated with Ficoll-Hypaque separation and co-stained with antibodies to CD19, CD5 and either BAFF-R (black outlined histograms) or an isotype-matched control antibody (filled histogram without outline). (B) Matched CD5+ (CLL) and CD5− (normal peripheral blood B) cell BAFF-R expression relative to the isotype-matched control antibody, ΔMFI. *p < 0.05.