Figure 5.

Example of dermal application of a tracer dye to mimic bimatoprost ophthalmic solution 0.03% to the upper eyelid margin using applicators results in the administration of a decreased dose compared with application as an eyedrop (Data on file; Allergan, Inc.). The above image was taken following administration of one drop (ie, 28–30 μL) of lissamine green as an eyedrop (right eye [top left, bottom left]) and one drop of lissamine green transferred to a sterile brush and applied to the dermal margin of the upper eyelid (left eye [top right, bottom right]).