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. 2010 Aug 4;3:275–280. doi: 10.2147/dmsott.s12136

Figure 1.

Figure 1

Suppression of maximally stimulated (44°C) dorsal skin perfusion by subject group pre- and post-training. “Non-PG” conditions include oral ingestion of aspirin and systemic suppression of PG synthesis by aspirin (left foot), while “non-PG/non-NO” conditions have inhibition of PG by aspirin and add local blockade of NO via microdialysis infusion of L-NAME, a NO synthase inhibitor (right foot). These results include oral aspirin ingestion in all subjects and have not yet been compared with normative data collected without aspirin. Subject groups are differentiated by both diabetes and training status.

Notes: Black bars, control subjects pre-training; gray bars, diabetic subjects pretraining; spotted bars, control subjects post-training; striped bars, diabetic subjects post-training. *P < 0.05 versus same group in non-PG; P < 0.01 versus same group in non-PG.

Abbreviations: PG, prostaglandins; NO, nitric oxide; L-NAME, (N(G)-nitro-larginine methyl ester); CON, controls; DM, diabetes mellitus.