. Author manuscript; available in PMC: 2011 Mar 3.

Published in final edited form as: J Pharmacol Exp Ther. 1982 Dec;223(3):750–756.

TABLE 3. Effect of GABA-mimetics on BEC and brain ethanol concentrations.

Ethanol (3.0 g/kg i.p.) was administered 60 min before sacrifice of the rats. Groups of eight animals also received saline, EOS, AOAA and DABA immediately after ethanol treatment or GAG 60 min before ethanol treatment by i.p. injection. Values represent the mean ± S.E.M. for four (brain) or eight (blood) observations.

GABA-Mimetic	Ethanol Conc.
GABA-Mimetic	Blood	Brain

mg/kg	μmol/ml	μmol/g
	75.2 ± 3.7	25.9 ± 3.5
EOS, 250	72.4 ± 3.7	21.3 ± 8.7
AOAA, 50	81.1 ± 2.6	29.3 ± 4.6
GAG, 100	74.3 ± 2.4	33.0 ± 4.3
DABA, 600	64.3 ± 3.3^**	21.5 ± 4.8

^**

P < .05 when compared with saline-ethanol treatment.