a. Exogenous angiogenin reduces rotenone-induced toxicity in SH-SY5Y cells in a cell-density-dependent manner. Cells were plated at either 30,000 or 50,000 cells/well and pretreated with angiogenin (100nM) prior to treatment with 0.2μM rotenone. n=4.
b. Angiogenin reduces rotenone toxicity in a different dopaminergic cell line, M17. n=4. *p<0.05 (one-way ANOVA followed by post-hoc Tukey’s test). Error bars reflect SEM