Table 3.
Inflammatory cells and inflammatory markers in serum of COPD patients (mean [SD])
| Males (n = 11) | Females (n = 30) | Pa | |
|---|---|---|---|
| Monocytes (×109/L) | 0.65 (0.15) | 0.63 (0.16) (n = 29) | 0.75 |
| Lymphocytes (×109/L) | 2.3 (1.1) | 2.3 (0.8) (n = 29) | 0.89 |
| Neutrophils (×109/L) | 3.5 (0.7) | 4.5 (1.2) (n = 29) | 0.019 |
| CRP (mg/mL) | 1.5 (1.5) | 4.9 (8.6) | 0.20 |
| IL-6 (pg/mL) | 3.6 (1.8) | 3.9 (2.5) | 0.75 |
| TNF-α (pg/mL) | 2.5 (2.5) | 1.6 (1.4) | 0.17 |
| IL-8 (pg/mL) | 15.1 (4.4) | 17.7 (7.7) | 0.30 |
| MPO (ng/mL) | 165 (114) | 153 (116) | 0.75 |
| NE (ng/mL) | 243 (201) | 246 (235) | 0.98 |
| ICAM-1 (ng/mL) | 683 (138) | 734 (172) | 0.38 |
| VCAM-1 (ng/mL) | 940 (202) | 993 (264) | 0.55 |
| E-selectin (ng/mL) | 75 (39) | 66 (28) (n = 29) | 0.39 |
a
Note: t-test.
Abbreviations: COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; ICAM, intracellular adhesion molecule; IL, interleukin; MPO, myeloperoxidase; NE, neutrophil elastase; SD, standard deviation; TNF, tumor necrosis factor; VCAM, vascular endothelial adhesion molecule.