Table 2.

Effect of amino acid residues on the virus susceptibility of neutralization by CHA5- and CHA5II-induced antiserum

Virus *	EC90 neutralization titers †
	CHA5 ‡	CHA5II
FJ	63 ± 15	200 ± 90
FJ P157S	200 ± 39	800 ± 132
FJ I190V	162 ± 27	598 ± 124
FJ S197P	158 ± 31	634 ± 103
AN	79 ± 18	224 ± 99
AN P157S	200 ± 37	500 ± 81
AN I190V	155 ± 32	462 ± 73
AN S197P	125 ± 26	317 ± 58

^*The HA of the virus was used to produce HA-pseudotyped virus.

^†The geometric means of EC₉₀ neutralization titer form more than three independent experiments.

^‡The DNA vaccine antigen was used to elicit antiserum.