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. 2010 Nov 16;19(3):479–489. doi: 10.1038/mt.2010.256

Figure 5.

Figure 5

Infiltration of human breast cancer tumors by mouse TAMs. (a) BT474-M1 and (b) HCC1954 tumors were established in CB17-SCID-beige mice. Tumors were harvested at 4 weeks after tumor cell injection and sections analyzed for vascularization using antibodies against mouse CD31 (endothelial marker); for tumor ECM, using antibodies against mouse laminin; for leukocyte infiltration using antibodies against mouse CD45; and for TAM infiltration using antibodies against mouse F4/80. Bar = 40 µm. TAM, tumor-associated macrophage.