Table 3. Associations of BMI, waist circumference and WHR with prostate cancer stage.
Reference group |
Stage
|
|||||
---|---|---|---|---|---|---|
Controls | Localised | OR (CI) | Advanced | OR (CI) | P for heterogeneity | |
BMI | ||||||
<25.0 | 1178 | 239 | 1.00 | 27 | 1.00 | |
25.0–29.9 | 2219 | 448 | 1.00 (0.84–1.19) | 39 | 0.77 (0.47–1.27) | |
⩾30.0 | 971 | 156 | 0.79 (0.63–0.98) | 20 | 0.94 (0.52–1.69) | |
Trend P-value | 0.053 | 0.745 | 0.74 | |||
Waist (cm) | ||||||
⩽91.4 | 1781 | 352 | 1.00 | 36 | 1.00 | |
91.5–99.1 | 1337 | 265 | 1.00 (0.84–1.19) | 25 | 0.90 (0.54–1.51) | |
>99.1 | 1465 | 265 | 0.91 (0.77–1.09) | 27 | 0.89 (0.54–1.48) | |
Trend P-value | 0.355 | 0.585 | 0.82 | |||
WHR | ||||||
⩽0.908 | 1514 | 291 | 1.00 | 28 | 1.00 | |
0.909–0.952 | 1437 | 303 | 1.10 (0.92–1.31) | 28 | 1.06 (0.62–1.80) | |
>0.952 | 1539 | 276 | 0.93 (0.78–1.11) | 32 | 1.14 (0.68–1.90) | |
Trend P-value | 0.473 | 0.681 | 0.53 |
Abbreviations: BMI=body mass index; CI=confidence interval; OR=odds ratio; WHR=waist-to-hip ratio.
Multinomial logistic regression model adjusted for age, survey centre, family history. All expected cell frequencies >5.
Groupings according to the WHO categorisation for BMI, and according to the distribution of controls for waist and WHR.