Table 2. Effect of percent density as measured by the Cumulus interactive threshold method on breast cancer risk, unadjusted, adjusted for BMI and adjusted for other significant risk factors.
|
OR (95% CI)
|
|||
|---|---|---|---|
| Density | Unadjusted | Adjusted for BMI | Multivariate adjusteda |
| 0–10 | 1.00 (−) | 1.00 (−) | 1.00 (−) |
| 11–25 | 1.04 (0.65–1.68) | 1.14 (0.70–1.85) | 1.12 (0.68–1.84) |
| 26–50 | 2.16 (1.39–3.35) | 2.66 (1.69–4.20) | 2.58 (1.62–4.12) |
| 51–75 | 3.59 (2.23–5.78) | 4.65 (2.83–7.64) | 3.94 (2.36–6.57) |
| 76–100 | 3.34 (1.55–7.20) | 5.74 (2.54–12.95) | 5.54 (2.38–12.90) |
Abbreviations: BMI=body mass index; CI=confidence intervals; OR=odds ratio.
Adjusted for BMI, age at menarche, no. of deliveries, age at first birth, OC use, HRT use and menopausal status.