Table 2. Age at diagnosis of oral cavity and oropharyngeal cancers (2005), trends in mean age over time (1982–2005) and changes in age standardised incidence over time (1982–2005)a.
|
Cancers diagnosed in 2005
|
Trends in age at diagnosis from 1982 to 2005
|
Changes in incidence from 1982 to 2005
|
|||||
|---|---|---|---|---|---|---|---|
| Sex | Cancer site | Count | Mean age at diagnosis (95% CI) | Percentage change per calendar year (95% CI) b | P-value | Percentage change per calendar year (95% CI) c | P-value |
| Males | Potentially HPV associated | 413 | 59.8 (58.8–60.9) | −0.06 (−0.11, −0.01) | 0.02 | 1.42 (1.08 to 1.76) | <0.01 |
| Tonsil | 193 | 57.4 (56.0–58.9) | −0.18 (−0.24, −0.11) | <0.01 | 1.39 (0.88 to 1.92) | <0.01 | |
| Base of tongue | 125 | 60.3 (58.5–62.2) | 0.02 (−0.05, 0.09 | 0.54 | 3.02 (2.27 to 3.78) | <0.01 | |
| Other oropharynx | 95 | 64.1 (61.8–66.4) | 0.09 (−0.01, 0.18) | 0.06 | −0.19 (−0.95 to 0.59) | 0.64 | |
| Comparison | 994 | 64.4 (63.7–65.2) | 0.12 (0.10, 0.15) | <0.01 | −1.69 (−1.96 to −1.42) | <0.01 | |
| Females | Potentially HPV associated | 118 | 63.6 (61.6–65.6) | 0.04 (−0.07, 0.14) | 0.47 | 1.04 (0.40 to 1.68) | <0.01 |
| Tonsil | 52 | 63.1 (60.2–66.1) | −0.03 (−0.17, 0.10) | 0.61 | 0.12 (−0.95 to 1.19) | 0.83 | |
| Base of tongue | 43 | 62.9 (59.5–66.3) | −0.01 (−0.15, 0.14) | 0.93 | 3.45 (2.21 to 4.70) | <0.01 | |
| Other oropharynx | 23 | 65.8 (60.8–70.7) | 0.20 (0.02, 0.39) | 0.03 | −0.24 (−1.57 to 1.10) | 0.72 | |
| Comparison | 324 | 66.9 (65.4–68.5) | 0.07 (0.03, 0.12) | <0.01 | −0.39 (−0.81 to 0.03) | 0.07 | |
Abbreviations: CI=confidence interval; HPV=human papillomavirus.
a
Squamous cell carcinomas.
b
Estimated by linear regression analysis.
c
Estimated using generalised linear models with a logarithmic link function.