Table 1. Independent prognosis factors in multivariate Cox proportional hazards analysis.
|
Disease-free survival
|
Overall survival
|
|||||
|---|---|---|---|---|---|---|
| Variables | P-value | HR | 95% CI | P-value | HR | 95% CI |
| Age | NS | — | — | NS | — | — |
| Gender | NS | — | — | NS | — | — |
| Alcohol habit | NS | — | — | NS | — | — |
| Smoking habit | 0.0070 | 3.365 | 1.387–8.165 | NS | — | — |
| Pathological T stage | 0.0001 | 5.505 | 2.417–12.540 | 0.0001 | 4.574 | 2.006–10.429 |
| Cellular differentiation | 0.0380 | 2.448 | 1.051–5.701 | NS | — | — |
| Mode of invasion | NS | — | — | NS | — | — |
| pN | NS | — | — | NS | — | — |
| ECS | 0.0001 | 7.345 | 3.269–16.501 | 0.0001 | 5.986 | 2.460–14.566 |
| CCND1 numerical aberration | NS | — | — | NS | — | — |
| EGFR numerical aberration | NS | — | — | NS | — | — |
Abbreviations: CI=confidence interval; ECS=extracapsular spread; EGFR=epidermal growth factor receptor gene; HR=hazard ratio; NS=not significant; pN=pathologically positive node.