Table 2. Tumour and normal tissue biopsy characteristics.
OSCC | Oral cavity controls | PSCC | Pharyngeal controls | Total | |
---|---|---|---|---|---|
Primary tumour location | |||||
Tongue | 15 | 8 | 23 | ||
Bucca | 2 | 8 | 10 | ||
Floor of mouth | 7 | 1 | 8 | ||
Gingiva | 5 | 5 | |||
Other oral cavity | 1 | 1 | |||
Tonsil | 5 | 14 | 19 | ||
Base of tongue | 10 | 1 | 9 | ||
Other pharynx | 4 | 7 | 11 | ||
Stage | |||||
I | 12 | 1 | 13 | ||
II | 8 | 4 | 12 | ||
III | 4 | 7 | 11 | ||
IVa and IVb | 6 | 5 | 11 | ||
Grade | |||||
Well differentiated | 5 | 2 | 7 | ||
Intermediate differentiated | 12 | 7 | 19 | ||
Poorly differentiated | 13 | 10 | 23 | ||
p16 positive | 3 | 0 | 10 | 0 | 13 |
In situ hybridisation positive | 1 | 0 | 6 | 0 | 7 |
PCR HPV positive | 3 | 0 | 6 | 1 | 9 |
HPV positive by two parameters | 1 | 0 | 8 | 0 | 9 |
Abbreviations: HPV=human papilloma virus; ND=not determined; OSCC=oral squamous cell carcinoma; PCR=polymerase chain reaction; PSCC=pharyngeal squamous cell carcinoma.