Table 3.
Final scores (mean and SD) and change scores (mean and 95% confidence interval) for the main outcome variables
| NS | D | PNS | M | F | p | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Final score (SD) | Change score (95% CI) | Final score (SD) | Change score (95% CI) | Final score (SD) | Change score (95% CI) | Final score (SD) | Change score (95% CI) | |||
| Pain 0–10 | 4.6 (2.4) | 1.30 (0.53, 2.07) | 3.8 (2.4) | 0.76 (0.13, 1.38) | 2.8 (2.1) | 2.57 (1.52, 3.63)a | 3.8 (2.1) | 0.72 (−0.11, 1.45) | 3.3 | 0.025 |
| RMDQ 0–24 | 8.7 (4.5) | 1.36 (−0.21, 2.92) | 5.4 (5.1) | 1.89 (0.62, 3.16) | 3.4 (3.0) | 5.34 (3.21, 7.48)b | 6.1 (4.5) | 0.79 (−0.71, 2.26) | 4.4 | 0.007 |
| GPC 1–7 | 3.29 (2.80, 3.77) | 3.13 (2.74, 3.52) | 2.25 (1.59, 2.91)c | 3.64 (3.18, 4.10) | 4.1 | 0.01 | ||||
Change scores of pain (numerical rating scale 1–10), disability (Roland Morris Disability Questionnaire 0–24) and patient perceived global change GPC (1 = completely recovered to 7 = worse than ever) are estimated marginal means adjusted for baseline pain intensity and disability. F and p values are from univariate analysis of covariance (ANCOVA)
NS neuropathic sensitization, D denervation, PNS peripheral nerve sensitization, M musculoskeletal
ap values for pair-wise comparisons (LSD): NS-PNS: 0.053; D-PNS: 0.002; PNS-M: 0.001; b p values for pair-wise comparisons (LSD): NS-PNS: 0.003; D-PNS: 0.007; PNS-M: 0.001; cp values for pair-wise comparisons (LSD): NS-PNS: 0.004; D-PNS: 0.015; PNS-M: < 0.001; all other pair-wise comparisons were not significant with p > 0.21