Table 3.

COMI and NRS back and neck, NRS leg and arm, by age group, by gender, by previous treatment, by flags and by medication

Variable	N	Mean and standard deviation
		COMI back	COMI neck	NRS back	NRS leg	NSR neck	NSR arm
Overall
Admission	60	5.0 ± 2.2	5.0 ± 2.1	4.6 ± 2.7	3.0 ± 2.9	4.5 ± 2.7	3.2 ± 2.8
First follow-up	60	3.5 ± 2.2	3.0 ± 2.0	3.0 ± 2.4	1.9 ± 2.6	2.4 ± 2.2	1.5 ± 2.0
Last follow-up	57	2.1 ± 2.4	2.0 ± 2.1	2.1 ± 2.5	1.2 ± 1.9	2.1 ± 2.5	1.8 ± 2.2
Age group
<40
Admission	21	3.9 ± 2.1	4.5 ± 2.1	3.8 ± 2.8	2.3 ± 2.9	4.1 ± 2.6	3.1 ± 2.5
First follow-up	21	2.6 ± 1.8	3.0 ± 1.9	2.1 ± 1.8	1.3 ± 2.3	2.5 ± 2.5	2.2 ± 2.3
Last follow-up	20	1.1 ± 1.6	1.5 ± 1.8	1.6 ± 2.0	0.3 ± 1.0	1.8 ± 2.2	1.5 ± 2.1
40–59
Admission	27	5.4 ± 2.0	5.7 ± 2.2	5.0 ± 2.5	3.1 ± 2.8	5.3 ± 2.8	3.3 ± 3.0
First follow-up	27	3.5 ± 2.1	2.8 ± 1.9	2.0 ± 2.0	1.7 ± 2.0	2.0 ± 1.7	0.9 ± 1.5
Last follow-up	26	2.8 ± 2.7	2.7 ± 1.9	2.8 ± 2.8	1.8 ± 2.0	2.7 ± 2.9	2.3 ± 2.5
≥60
Admission	12	6.1 ± 2.1	4.8 ± 2.1	5.3 ± 3.0	4.2 ± 3.0	3.4 ± 2.7	3.0 ± 3.5
First follow-up	12	4.9 ± 2.6	3.3 ± 2.9	4.3 ± 3.3	3.6 ± 3.5	2.7 ± 2.4	1.2 ± 1.0
Last follow-up	11	2.4 ± 2.3	2.3 ± 2.9	1.5 ± 2.3	1.5 ± 2.3	2.0 ± 2.8	1.5 ± 2.3
Gender
M
Admission	20	5.2 ± 2.7	5.2 ± 2.6	4.9 ± 2.8	2.8 ± 2.8	4.5 ± 2.9	1.1 ± 1.9
First follow-up	20	3.6 ± 2.3	2.1 ± 1.6	3.1 ± 2.5	1.3 ± 2.2	1.4 ± 1.2	0.8 ± 1.2
Last follow-up	19	2.8 ± 2.7	0.4 ± 0.7	2.6 ± 2.9	1.4 ± 1.9	0.6 ± 0.8	0.3 ± 0.5
F
Admission	40	4.9 ± 1.9	4.9 ± 2.1	4.5 ± 2.8	3.2 ± 3.0	4.5 ± 2.7	3.7 ± 2.7
First follow-up	40	3.4 ± 2.2	3.2 ± 2.1	2.9 ± 2.3	2.3 ± 2.7	2.6 ± 2.3	1.8 ± 2.1
Last follow-up	38	1.8 ± 2.1	2.6 ± 2.2	1.9 ± 2.3	1.1 ± 1.9	2.5 ± 2.7	2.2 ± 2.3
Previous treatment
No
Admission	17	6.0 ± 2.2	4.0 ± 2.4	5.5 ± 3.1	3.1 ± 2.9	4.0 ± 3.3	1.5 ± 2.1
First follow-up	17	2.8 ± 2.3	1.6 ± 1.2	2.4 ± 2.8	1.6 ± 2.4	1.1 ± 1.4	0.9 ± 1.2
Last follow-up	15	1.7 ± 1.8	0.8 ± 1.1	1.2 ± 2.0	0.4 ± 0.9	0.9 ± 1.5	1.1 ± 1.8
Yes
Admission	43	4.6 ± 2.1	5.3 ± 2.0	4.3 ± 2.5	3.0 ± 2.9	4.6 ± 2.6	3.6 ± 2.8
First follow-up	43	3.7 ± 2.2	3.3 ± 2.1	3.2 ± 2.1	2.0 ± 2.6	2.7 ± 2.3	1.7 ± 2.1
Last follow-up	42	2.3 ± 2.5	2.4 ± 2.2	2.5 ± 2.6	1.5 ± 2.1	2.5 ± 2.7	2.0 ± 2.3
Flag(s)a
No
Admission	49	4.8 ± 2.2	4.8 ± 2.2	4.4 ± 2.7	2.9 ± 2.9	4.3 ± 2.8	3.1 ± 2.9
First follow-up	49	3.2 ± 2.1	2.9 ± 2.1	2.7 ± 2.3	1.8 ± 2.5	2.4 ± 2.3	1.4 ± 2.0
Last follow-up	48	2.1 ± 2.4	1.8 ± 2.0	2.2 ± 2.6	1.2 ± 1.9	1.7 ± 2.3	1.5 ± 2.1
Yes
Admission	11	6.1 ± 1.9	6.5 ± 1.2	5.6 ± 2.9	3.7 ± 2.9	6.3 ± 1.5	3.8 ± 2.1
First follow-up	11	4.8 ± 2.4	3.5 ± 1.3	4.4 ± 2.2	2.5 ± 2.8	2.3 ± 1.3	2.8 ± 1.7
Last follow-up	9	2.5 ± 2.2	3.9 ± 1.9	2.0 ± 1.8	1.3 ± 1.9	5.3 ± 2.1	3.8 ± 2.4
Medication
No
Admission	31	4.5 ± 1.9	4.7 ± 2.2	4.0 ± 2.8	2.6 ± 2.8	4.0 ± 2.7	3.5 ± 2.8
First follow-up	31	2.7 ± 1.5	2.9 ± 2.1	2.3 ± 1.8	1.8 ± 2.3	2.2 ± 2.1	1.8 ± 2.2
Last follow-up	29	1.2 ± 1.2	2.3 ± 2.3	1.4 ± 1.9	1.0 ± 1.8	2.5 ± 2.6	2.3 ± 2.5
Yes
Admission	29	5.6 ± 2.3	5.6 ± 2.0	5.3 ± 2.6	3.5 ± 2.9	5.4 ± 2.5	2.5 ± 2.6
First follow-up	29	4.2 ± 2.6	3.1 ± 2.1	3.7 ± 2.7	2.1 ± 2.8	2.7 ± 2.4	1.0 ± 1.4
Last follow-up	28	3.1 ± 2.9	1.6 ± 1.8	2.9 ± 2.9	1.4 ± 2.0	1.4 ± 2.3	0.8 ± 1.3

Table 3: first follow-up took place at end of therapy or at 6 weeks after admission at the latest

Last follow-up took place exactly 12 weeks after first follow-up

COMI Core Outcome Measures Index, NRS Numerical Rating Scale, Flags Biomedical, psychosocial, socioeconomic, psychiatric and occupational risk factors

^aCan be one or several flags at time point T1/T2/T3