Table 6.
Selected prior published studies on ODPE for infected TKA
| Authors/study | Subjects (knees) | Mean followup (years) | Average duration of symptoms success/failure (days) | Average time from index to débridement (range) | Number of knees less than 1 month from index surgery | Number infected with Staphylococcus aureus | Failure rate for S. aureus | Successful salvage of components |
|---|---|---|---|---|---|---|---|---|
| Burger et al. [3] | 39 | 4.1 | 4.4/117 | N/A | N/A | 20 (51%) | 85% | 17.9% (7/39 knees) |
| Deirmengian et al. [5] | 31 | 4.0 | 7.6/10.1 | 24 months (0.5-84) | N/A | 13 (42%) | 92% | 35% (11/31 knees)* |
| Mont et al. [15] | 24 | 5.0 | 9.9/26† | 23 months (6-71)‡ | 10 (42%) | 12 (50%) | 8% | 83% (20/24 knees)§ |
| Hartman et al. [10] | 33 | 4.5 | 18.6/10.5 | 11 months (N/A) | 11 (33%) | 13 (39%) | 69% | 39% (13/33 knees) |
| Schoifet and Morrey [16] | 31 | 8.8 | 21/36 | N/A | 9 (29%) | 16 (52%) | 88% | 23% (7/31 knees) |
| Gardner et al. [current study] | 44 | 5.0 | 7.8/8.8 | 13 months (0.2-84) | 10 (23%) | 17 (39%) | 71% | 57% (25/44 knees) |
* Five of 11 continued on suppressive antibiotics for control of infection; †data only available for 14 of 24 knees; ‡this represents time from index surgery to débridement for 14 of the 24 knees; the other 10 knees were less than 1 month from index; §inclusion criteria were less than 30 days from index or less than 30 days of symptoms and multiple débridements were performed; ODPE = open débridement with polyethylene liner exchange; N/A = data not available within the study.