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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Muscle Nerve. 2010 Jul;42(1):112–119. doi: 10.1002/mus.21626

Figure 4. Discrepancies between automated and manual SGNFD in a subject with diabetes.

Figure 4

The sweat gland from the distal thigh of a subject with diabetes is shown in (A). Note the thickened nerve fibers that are highlighted in red by the automated counting method in (B) that give an overall high SGNFD. The manual counting method has fewer intercept points, shown in red in (C), because the thickened nerve fibers are not as evenly distributed throughout the sweat gland, reducing the SGNFD. Scale bar = 50 μm.