Table 3.
Characteristics of women with POI (n = 174) with and without lifetime history of major and minor depression
| Major depression (n = 95) | Minor depression (n = 22)a | No lifetime depression (n = 57) | |
|---|---|---|---|
| Age (yr) | 31.8 (4.9) | 32.6 (6.0) | 30.9 (5.8) |
| No. married | 63 (66%) | 17 (77%) | 42 (74%) |
| Height (cm) | 165.2 (6.8) | 164.4 (6.9) | 163.9 (8.4) |
| BMI (kg/m2) | 23.8 (3.5) | 23.3 (3.3) | 23.8 (3.4) |
| Years of education | 16.3 (2.0) | 16.6 (1.7) | 16.0 (2.4) |
| Plasma FSH (IU/liter) | 83.5 (36.0) | 87.5 (36.7) | 83.5 (35.2) |
| Age at menarche (yr) | 12.9 (1.6) | 12.7 (1.1) | 12.5 (1.3) |
| Age at POI diagnosis (yr) | 28.4 (6.6) | 30.0 (6.3) | 28.4 (6.8) |
| Age at MCI onset (yr) | 23.8 (7.9) | 26.1 (8.2) | 24.8 (7.8) |
| Duration of MCI before POI diagnosis (yr) | 5.2 (5.9) | 4.4 (5.2) | 4.2 (4.8) |
| No. of smokers | 3 (3.1%) | 1 (4.5%) | 6 (10.5%) |
| No. ever treated with antidepressants | 45 (47%)b | 1 (4.5%) | 2 (3.5%) |
| No. on thyroid treatment | 10 (10.5%) | 0 | 7 (12.2%) |
| No. on HT | 74 (78%) | 16 (73%) | 42 (74%) |
Data are expressed as mean (sd) unless otherwise indicated.
a
Two women included in this group met criteria for dysthymic disorder.
b
χ2 = 24.6; P < 0.001. Otherwise, all group comparisons were nonsignificant.