Table I.

Total cell numbers in lymphoid organs of 4–6 month old LMP1+Sle1 vs. LMP1+Sle3 mice and non-transgenic littermates

			LMP1−Sle1	LMP1+SIe1	LMP1−Sle3	LMP1+Sle3
Spleen
	Total cells (x 106)		204.6 ± 81	329.5 ± 201	89.1 ± 30.7	75.8 ± 15.9
	B cells		65.6 ± 28.8	100.3 ± 55	25.3 ± 9.8	22.6 ± 3.7
	T cells		58.7 ± 29.8	85.6 ± 50.6	25.8 ± 10.2	22.8 ± 3.4
	CD4+ T cells		31.5 ± 11.2	48.6 ± 33.1	16 ± 7.5	13.8 ± 3.7
		naive	10.4 ± 5.2	7.2 ± 5.3	7.2 ± 3.3	5.4 ± 0.4
		activated	14.4 ± 8.1	30.5 ± 23.7*	5.4 ± 2.8	5.4 ± 2.4
	CD8+ T cells		14.9 ± 6.5	15.1 ± 10.8	8.1 ± 2.1	7.2 ± 1.04
		naive	8.8 ± 4.9	8.3 ± 8.3	5 ± 1.7	4.4 ± 0.6
		activated	1.5 ± 0.6	3.1 ± 2.5	0.61 ± 0.2	0.81 ± 0.05
		memory	1.8 ± 0.61	2.48 ± 2.9	0.66 ± 0.21	0.87 ± 0.15
LN
	Total cells		50.6 ± 29.3	82.8 ± 50.1*	40.6 ± 42.8	38.4 ± 2.3
	B cells		15.4 ± 9.2	26.6 ± 15.4*	11.9 ± 14.2	11.2 ± 2.6
	T cells		20.9 ± 13.3	27.5 ± 18.7*	17 ± 17.4	17.7 ± 0.4
	CD4+ T cells		10.4 ± 6.3	15.3 ± 10.5	8.4 ± 7.9	8 ± 0.3
		naive	7 ± 4.2	9.1 ± 7.2	5.7 ± 5.2	8.1 ± 4.5
		activated	1.3 ± 0.9	3.1 ± 1.8*	1 ± 1.02	2.1 ± 1.2
	CD8+ T cells		9.3 ± 4.8	13 ± 9.9	7.4 ± 7.1	7.04 ± 0.9
		naive	6.8 ± 3.8	9.2 ± 7.4	5.7 ± 5.2	5.1 ± 2
		activated	0.33 ± 0.3	0.65 ± 0.3*	0.23 ± 0.28	0.26 ± 0.03
		memory	0.81 ± 0.54	1.5 ± 1.4	0.51 ± 0.5	0.6 ± 0.004

^*= p < 0.05 by Mann-Whitney U test