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. Author manuscript; available in PMC: 2011 Apr 1.

Published in final edited form as: J Immunol. 2010 Sep 1;185(7):4053–4062. doi: 10.4049/jimmunol.0904065

Table IV.

Frequency of Activated T cells and B220+CD86+ cells in lymphoid organs of 12 month old LMP1+Sle1 vs. LMP1+Sle3 mice and non-transgenic littermates

			LMP1⁻Sle1	LMP1⁺Sle1	LMP1⁻Sle3	LMP1⁺Sle3

Spleen
	B220⁺CD86⁺		35.5 ± 3.1	39.4 ± 3.7	28.6 ± 2.9	29.8 ± 4.1
	CD4⁺ T cells
		naive	17.9 ± 11.8	1.8 ± 1.1^*	36 ± 7.8	17.9 ± 7.1^*
		activated	57 ± 13	81.6 ± 1.8^*	40 ± 6.3	57 ± 7^*
	CD8⁺ T cells
		naive	36.4 ± 5.8	12.4 ± 6.8^*	44.5 ± 4.4	33.8 ± 9.3
		activated	16.9 ± 4	30.4 ± 5^*	16.6 ± 2.6	17.5 ± 3.7
		memory	26.6 ± 3.1	19.9 ± 11.3	23 ± 4	32.7 ± 10

LN

	B220⁺CD86⁺		30.2 ± 3.1	39.5 ± 4.1^*	21 ± 2.6	26.1 ± 7.4
	CD4⁺ T cells
		naive	31.5 ± 10	13.8 ± 2^*	51.3 ± 3.1	32 ± 9^*
		activated	45 ± 10	60 ± 2^*	24.1 ± 2.3	43.1 ±7.4^*
	CD8⁺ T cells
		naive	52.2 ± 7.5	28 ± 6.9^*	63.4 ± 3.8	46 ± 5.1^*
		activated	15.1 ± 4.5	23.6 ± 7.3	8.1 ± 1.6	17.1 ± 3.4^*
		memory	22.5 ± 5	38.5 ± 3.7^*	19.6 ± 2.6	25.5 ± 3^*

^*

= p < 0.05 by two-tailed Student’s t-test