Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Mar 3;7(3):e1001319. doi: 10.1371/journal.pgen.1001319

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Mailund et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

The figure shows the probability of the two neighboring nucleotides being linked in the single-sequence CTMC and how this probability evolves over time. The probability for being unlinked is, of course, one minus the probability of being linked, since the CTMC has only two states. The two different lines correspond to two different coalescence rates. For population 1, the coalescence rate is set to 1 (so the x-axis is in units of generations for this species), while for population 2 the coalescence rate is half that, corresponding to population 2 having twice the effective population size of population 1. The recombination rate is set to . Assuming of 20,000 for population 1 and 40,000 for population 2, and a generation time of 20 years, this corresponds to 1 cM/Mbp and 1 unit on the x-axis corresponds to 400,000 years. The separation time we infer for the orangutan sub-species is around on the x-axis, where the system is still far from equilibrium.

Inline graphic — The figure shows the probability of the two neighboring nucleotides being linked in the single-sequence CTMC and how this probability evolves over time. The probability for being unlinked is, of course, one minus the probability of being linked, since the CTMC has only two states. The two different lines correspond to two different coalescence rates. For population 1, the coalescence rate is set to 1 (so the x-axis is in units of generations for this species), while for population 2 the coalescence rate is half that, corresponding to population 2 having twice the effective population size of population 1. The recombination rate is set to . Assuming of 20,000 for population 1 and 40,000 for population 2, and a generation time of 20 years, this corresponds to 1 cM/Mbp and 1 unit on the x-axis corresponds to 400,000 years. The separation time we infer for the orangutan sub-species is around on the x-axis, where the system is still far from equilibrium.