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. 2011 Mar 3;7(3):e1001095. doi: 10.1371/journal.pcbi.1001095

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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We observed that PTEN might exert its influence on target genes (the endpoints of each causal path) through prominent transcription factors such as TP53, MYC and MYB.