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. 2011 Mar 3;7(3):e1001097. doi: 10.1371/journal.pcbi.1001097

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Bar-On et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Two snapshots taken from a 20-ns-simulation of munc18a^F115E demonstrate the closure of the cavity between domains 3a and 1 during the simulation of this mutant as well. A) t = 0, B) t = 20 ns, the cavity area is framed in both A and B. C) Measurement of the distance between the centers of mass of domains 3a and 1 during the Munc18a^F115E simulation.