Table 1. Functional Annotation Chart, performed using DAVID Bioinformatics tool.

KEGG pathways	Genes	p-Value	Benjamini (corrected p-value)
Pathways in cancer	BCL2, E2F1, E2F3, CASP3, EGFR, VEGF, COL4A1, COL4A2, CD1, CDK6, p21, p27, CDKI2A, JUN, MET, MSH2, RAS, PTEN, RB1, TGFb2, MYC	3.8E-11	1.8E-9
Bladder cancer	E2F1, E2F3, EGFR, CD1, CDKI2A, CDKI1A, RAS, RB1, VEGF, MYC, THBS1	8.7E-12	8.4E-10
Chronic myeloid leukemia	E2F1, E2F3, CD1, CDK6, CDKI1A, CDKI1B, CDKI2A, RAS, RB1, TGFb2, MYC	3.7E-9	9.1E-8
Small cell lung cancer	BCL2, E2F1, E2F3, COL4A1, COL4A2, CD1, CDKI1B, CDK6, PTEN, RB1, MYC	1.2E-8	2.3E-7
Melanoma	E2F1, E2F3, CD1, CDKI2A, CDKI1A, CDK6, EGFR, RAS, RB1, PTEN, MET	2.2E-9	7.0E-8
Glioma	E2F1, E2F3, CD1,CDKI2A, CDKI1A, CDK6, EGFR, RAS, RB1, PTEN	1.3E-8	2.1E-7

We report the Gene Ontology (GO) Terms and KEGG pathways Over-represented among Joint Target Genes, performed using DAVID Bioinformatics tool. For each row the corresponding Benjamini (corrected for multiple testing) as well as the raw hypergeometric p-values are indicated.