. 2011 Mar 3;6(3):e17676. doi: 10.1371/journal.pone.0017676

Table 2. Differentially expressed actin and focal adhesion associated genes in MOSE cell stages.

Gene symbol	Gene Name	Accession Number	I/E	p-val	L/E	p-val
Actin
Acta1	alpha actin 1	NM_009606	−2.2	0.0547	−2.6	0.0487
*Acta2*	*alpha actin 2*	*NM_007392*	*−2.8*	*0.0698*	*−19.3*	*0.0139*
*Actg1* ^*	*gamma actin 1*	*NM_009609*	*−2.1*	*0.0331*	*−2.1*	*0.0331*
*Actg2*	*gamma actin 2*	*NM_009610*	*−8.6*	*0.0742*	*−12.6*	*0.0552*
Focal Adhesion
*Actn1*	*actinin, alpha 1*	*NM_134156*	*−3.8*	*0.0454*	*−5.3*	*0.0347*
Fblim1	filamin binding LIM protein 1	NM_133754	−1.6	0.1103	−2.5	0.0282
Itga7	integrin alpha 7	NM_008398	−5.3	0.0179	−7.1	0.0116
Itgav	Integrin alpha V	NM_008402	−3.7	0.0079	−1.5	0.2389
Itgb1	Integrin beta 1	NM_010578	−2.1	0.0441	1.1	0.7088
Itgb2	integrin beta 2	NM_008404	7.2	0.0059	4.1	0.0365
Itgb5	integrin beta 5	NM_010580	1.7	0.0347	2.7	0.0313
Lasp1	LIM and SH3 protein 1	NM_010688	−1.2	0.2772	−2.7	0.0015
Nck2	non-catalytic region tyrosine kinase adaptor protein 2	NM_010879	1.6	0.0027	2.7	0.0097
Parva	parvin, alpha	NM_020606	−2.0	0.0646	−3.3	0.0314
*Pxn*	*Paxillin*	*NM_133915*	*1.4*	*0.0765*	*2.2*	*0.0094*
Tgfb1i1	TGF beta 1 induced transcript 1	NM_009365	−3.7	0.0668	−49.0	0.0251
*Tns1*	*tensin 1*	*NM_027884*	*−2.3*	*0.0520*	*−5.1*	*0.0162*
*Vcl*	*Vinculin*	*NM_009502*	*−2.4*	*0.0658*	*−3.8*	*0.0355*
Zyx	Zyxin	NM_011777	−3.8	0.0383	−4.5	0.0317

List of genes differentially regulated (fold differences ≥2, p<0.05) which are structural or regulatory proteins of the actin cytoskeleton. Genes in italics were analyzed by qRT-PCR, in bold were validated to change significantly between MOSE-E and MOSE-L cells, and those not in bold were validated to change significantly (p<0.05) between MOSE-E and MOSE-I cells.

*denotes genes that are already changed in MOSE-I and maintain these expression levels in MOSE-L.