Table 4. Differentially Expressed Microtubule and Microtubule Associated Genes in MOSE cell stages.
| Gene Symbol | Gene Name | Accession Number | I/E | p-val | L/E | p-val |
| Microtubule | ||||||
| Tuba4a | tubulin, alpha 4A | NM_009447 | 1.5 | 0.0301 | −2.2 | 0.0146 |
| Tubb2a | tubulin, beta 2a | NM_009450 | −1.2 | 0.4725 | −3.5 | 0.0007 |
| Tubb2b | tubulin, beta 2b | NM_023716 | −2.8 | 0.0200 | −3.3 | 0.0144 |
| Tubb2c | tubulin, beta 2c | NM_146116 | 1.2 | 0.2601 | −2.1 | 0.0261 |
| Tubb3 | tubulin, beta 3 | NM_023279 | 1.5 | 0.1902 | −3.0 | 0.0362 |
| Tubb6 | tubulin, beta 6 | NM_026473 | −1.2 | 0.0437 | −4.7 | 0.0013 |
| Microtubule Binding and Regulation | ||||||
| Aspm+ | asp (abnormal spindle)-like | NM_009791 | −1.7 | 0.0467 | −3.0 | 0.0300 |
| Cenpe+ | centromere protein E | NM_173762 | −2.2 | 0.0246 | −3.7 | 0.0171 |
| Ckap2+ | cytoskeleton associated protein 2 | NM_001004140 | 1.1 | 0.3932 | −2.2 | 0.0324 |
| Ckap2l | cytoskeleton associated protein 2-like | NM_181589 | 1.0 | 0.2245 | −2.8 | 0.0050 |
| Ckap4 | cytoskeleton-associated protein 4 | NM_175451 | −1.7 | 0.0290 | −3.0 | 0.0077 |
| Dnm2 | dynamin 2 | NM_001039520 | 1.7 | 0.2847 | 4.4 | 0.0049 |
| Dync1i1 | dynein cytoplasmic 1 intermediate chain 1 | NM_010063 | 1.4 | 0.4035 | 6.1 | 0.0450 |
| Incenp+ | inner centromere protein | NM_016692 | 1.1 | 0.1875 | −2.1 | 0.0379 |
| Jub+ | Ajuba | NM_010590 | −3.6 | 0.0390 | −3.2 | 0.0451 |
| Kif1b | kinesin family member 1B | NM_008441 | −1.9 | 0.0304 | −2.3 | 0.0195 |
| Kif18a + | kinesin family member 18A | NM_139303 | −1.2 | 0.2028 | −2.8 | 0.0062 |
| Kif20a + | kinesin family member 20A | NM_009004 | 1.2 | 0.1513 | −2.7 | 0.0331 |
| Kif21a | kinesin family member 21A | NM_016705 | 1.5 | 0.2060 | 2.4 | 0.0334 |
| Kif22 + | kinesin family member 22 | NM_145588 | 1.0 | 0.2291 | −2.7 | 0.0178 |
| Kif23 + | kinesin family member 23 | NM_024245 | −1.2 | 0.0970 | −3.4 | 0.0082 |
| Kif26b | kinesin family member 26B | NM_001161665 | 1.0 | 0.9068 | −3.9 | 0.0102 |
| Kif2c | kinesin family member 2C | NM_134471 | −1.2 | 0.0918 | −2.9 | 0.0211 |
| Kif4+ | kinesin family member 4 | NM_008446 | −1.4 | 0.0966 | −2.1 | 0.0306 |
| Klc1 | kinesin light chain 1 | NM_008450 | −1.4 | 0.0455 | −2.6 | 0.0009 |
| Klc4 | kinesin light chain 4 | NM_029091 | 1.3 | 0.3611 | 3.1 | 0.0015 |
| Lats2+ | large tumor suppressor 2 | NM_015771 | −3.4 | 0.0035 | −2.7 | 0.0058 |
| Mtap6 | microtubule-associated protein 6 | NM_010837 | −3.0 | 0.0012 | −15.7 | 0.0004 |
| Ndn | necdin | NM_010882 | −3.7 | 0.0124 | −26.8 | 0.0017 |
| Ninl* | ninein-like | NM_207204 | −2.6 | 0.0068 | −2.2 | 0.0029 |
| Pea15a | phosphoprotein enriched in astrocytes 15A | NM_011063 | −1.3 | 0.2698 | −2.9 | 0.0179 |
| Prc1+ | protein regulator of cytokinesis 1 | NM_145150 | −1.4 | 0.0245 | −2.6 | 0.0158 |
| Shroom3 | shroom family member 3 | NM_015756 | −1.2 | 0.3917 | 2.8 | 0.0115 |
| Tbcel | tubulin folding cofactor E-like | NM_173038 | 1.2 | 0.1501 | 3.5 | 0.0292 |
| Vav2 | vav 2 guanine nucleotide exchange factor | NM_009500 | −2.1 | 0.0226 | −4.0 | 0.0062 |
List of genes differentially regulated (fold differences ≥2, p<0.05) which are structural or regulatory proteins of the microtubule network. Genes in italics were analyzed by qRT-PCR and those in bold were validated to change significantly.
*denotes genes that are already changed in MOSE-I and maintain these expression levels in MOSE-L, + denotes genes that have products involved in chromosome congression, segregation, and/or cytokinesis.